Prognostic value of <em>SOX2</em>, CyclinD1, P53, and ki-67 in patients with esophageal squamous cell carcinoma
نویسندگان
چکیده
منابع مشابه
Prognostic value of p53 in renal cell carcinoma
Background and Objectives: RCC is one of the most common genitourinary cancers. Accurate prediction of prognosis would be valuable for adjuvant trial design, counseling and effectively scheduling follow up visits. P53 is a tumor suppressor gene that expresses a protein that involved in both cell-cycle ar...
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Recent technical and scientific advances on oncology allowed increase of patients’ survival, sequelae reduction and prevention of other tumours, including second primary tumours (SPT). Indeed, some individuals with head and neck cancer manage to survive the first primary tumour, but cannot resist the second. For these reasons, studies to evaluate the factors related to SPT development of are gr...
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Telomerase activation is one of the main pathways to immortalize cancer cells. In many kinds of cancer cells, this special reverse transcriptase stabilizes and elongates telomeres and prevents telomere erosion that naturally occurs in every cell division. Esophageal cancer is the fifth most frequent cause of cancer death worldwide, and is highly associated with alcohol, smoking, cultural ha...
متن کاملExpression analysis of CD44 isoforms S and V3, in patients with esophageal squamous cell carcinoma
Objective(s): CD44 is a member of the cell adhesion molecules family. Naturally, CD44S, along with CD44V3 influence the cell motility, migration, and adhesion, while in tumor cells they lead to tumor invasion, progression, and metastasis. The purpose of this research is to evaluate the CD44S and CD44V3 expression in Esophageal Squamous Cell Carcinoma (ESCC) and to reveal their correlations wit...
متن کاملKi-67 and p53 correlation prognostic value in squamous cell carcinomas of the oral cavity and tongue.
UNLABELLED Epidermoid carcinomas represent from 90% to 95% of oral cavity malignant neoplasias, making up 13,470 cases/year. AIMS To correlate p53 and Ki-67 expressions in mouth and tongue carcinomas with lymph node status, gender, histological grade, tumor volume and pathological stage. MATERIALS AND METHODS We carried out a retrospective study of 28 cases of mouth and tongue epidermoid ca...
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ژورنال
عنوان ژورنال: OncoTargets and Therapy
سال: 2018
ISSN: 1178-6930
DOI: 10.2147/ott.s160066